What drug class is esomeprazole?

esomeprazole is classified as a Proton Pump Inhibitors.

Is there a generic version of esomeprazole?

Yes, generic versions of esomeprazole are available. See the Exact Equivalents section above for FDA-rated generic alternatives.

How does esomeprazole work?

esomeprazole mechanism of action information is available in the Drug Information section of this page.

Esomeprazole

Also sold as: Nexium, Vimovo

Proton Pump InhibitorsPrescription OnlyGeneric Available

Dose Equivalency Guide

Approximate equivalent doses within Proton Pump Inhibitors

Drug	Low Dose	Medium Dose	High Dose	Notes
omeprazole	10 mg	20 mg	40 mg	OTC available; take 30-60min before meals
esomeprazole (this drug)	10 mg	20 mg	40 mg	S-isomer of omeprazole; similar efficacy
lansoprazole	15 mg	30 mg	30 mg BID	OTC available
pantoprazole	20 mg	40 mg	40 mg BID	Fewest drug interactions of PPIs
rabeprazole	10 mg	20 mg	20 mg BID	Fastest onset of action
dexlansoprazole	30 mg	30 mg	60 mg	Dual-release; can be taken without regard to food

Source: AGA Clinical Practice Guidelines

View Proton Pump Inhibitors dose reference chart →

Related Medications

Important: Only drugs listed as "Exact Equivalents" (FDA AB-rated) are confirmed interchangeable. All other listings are for informational reference only and do NOT indicate that drugs can be substituted without a physician's explicit guidance.

Same Pharmacologic Class

These drugs share a pharmacologic classification but are NOT interchangeable. Listing here does not imply clinical equivalence. A physician must evaluate each drug individually for the patient's specific condition.

Classification: Proton Pump Inhibitors (source: RxClass/NLM)

Insurance Coverage User-Reported

Community Data Disclaimer: Insurance coverage information below was submitted by RxSaurus users and has not been verified by RxSaurus. Coverage varies by plan, year, geography, and individual circumstances. Drug formulary status, prior authorization requirements, and tier placements change frequently. Always verify coverage directly with the patient's insurance plan or pharmacy benefits manager before prescribing or dispensing.

No community coverage data yet for esomeprazole.

Coverage data submission coming soon.

Drug Information

Indications & Uses

Uses treats frequent heartburn (occurs 2 or more days a week) not intended for immediate relief of heartburn; this drug may take 1 to 4 days for full effect

Dosage & Administration

Directions adults 18 years of age and older this product is to be used once a day (every 24 hours), every day for 14 days may take 1 to 4 days for full effect 14-Day Course of Treatment • swallow 1 tablet with a glass of water before eating in the morning • take every day for 14 days • do not take more than 1 tablet a day • swallow whole. Do not crush or chew capsules. • do not use for more than 14 days unless directed by your doctor Repeated 14-Day Courses (if needed) • you may repeat a 14-day course every 4 months • do not take for more than 14 days or more often than every 4 months unless directed by a doctor children under 18 years of age: ask a doctor before use. Heartburn in children may sometimes be caused by a serious condition .

Warnings & Precautions

Warnings Allergy alert : Do not use if you are allergic to esomeprazole. Esomeprazole may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If an allergic reaction occurs, stop use and seek medical help right away.

Verify with Primary Sources

Always verify clinical information with authoritative sources.

DailyMed (NLM/NIH)FDA-approved drug labeling↗FDA Orange BookTherapeutic equivalence data↗RxNorm (NLM/NIH)Drug nomenclature & relationships↗