Oxymetazoline
Also sold as: Afrin, Allerest 12 Hour Nasal Spray, Dristan 12-Hour Nasal Spray, Duramist Plus, Neo-Synephrine 12 Hour (+9 more)
Related Medications
These drugs share a pharmacologic classification but are NOT interchangeable. Listing here does not imply clinical equivalence. A physician must evaluate each drug individually for the patient's specific condition.
Classification: Imidazolines (source: RxClass/NLM)
Insurance Coverage User-Reported
No community coverage data yet for oxymetazoline.
Coverage data submission coming soon.
Drug Information
Indications & Uses
Uses temporarily relieves nasal congestion due to a cold, hay fever, or other upper respiratory allergies sinus congestion and pressure
Dosage & Administration
Directions Remove protective cap. Before using for the first time, prime the pump by firmly depressing its rim several times. Hold container with thumb at base and nozzle between first and second fingers. Without tilting your head, insert nozzle into nostril. Fully depress rim with a firm, even stroke and inhale deeply. adults & children 6 yrs. & older (with adult supervision): 2 or 3 sprays in each nostril, not more often than every 10 to 12 hours. Do not exceed 2 doses in 24 hours. children 2 to under 6 yrs.: ask a doctor children under 2 yrs.: do not use
Warnings & Precautions
Warnings For external use only; avoid contact with eyes. Do not use by mouth in nostrils on wounds or damaged skin with tight bandages Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes trouble urinating due to enlarged prostate gland When using this product, do not do not exceed recommended dosage do not use this product for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen temporary discomfort such as burning, stinging, sneezing, or increased nasal discharge may occur use of this container by more than one person may spread infection Stop use and ask a doctor if symptoms persist. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Verify with Primary Sources
Always verify clinical information with authoritative sources.
Medical Disclaimer: Information on this page is sourced from FDA-approved labeling data and is for educational reference only. It does not constitute medical advice. This information does not establish a provider-patient relationship. Always verify with current prescribing information and consult a licensed healthcare professional before any clinical decision. Read full disclaimer.
Data sourced from RxNorm (NLM/NIH), FDA Orange Book, OpenFDA, DailyMed. Last updated: 2026-03-02.