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Albumin microspheres, human vs Perflutren

Side-by-side drug comparison

Perflutren(Optison Perflutren Protein-Type A Microspheres)
Drug Class
Ultrasound Contrast Activity
Ultrasound Contrast Activity
Mechanism of Action
12.1 Mechanism of Action The OPTISON microspheres create an echogenic contrast effect in the blood. The acoustic impedance of the OPTISON microspheres is much lower than that of the blood. Therefore, impinging ultrasound waves are scattered and reflected at the microsphere-blood interface and ultimately may be visualized in the ultrasound image. At the frequencies used in adult echocardiography (2 MHz to 5 MHz), the microspheres resonate which further increases the extent of ultrasound scattering and reflection.
Dosage Form / Route
Indications
OPTISON is indicated for use in adult and pediatric patients with suboptimal echocardiograms to opacify the left ventricle and to improve the delineation of the left ventricular endocardial borders. OPTISON is an ultrasound contrast agent indicated for use in adult and pediatric patients with...
Prescription Status
Prescription
Prescription
Generic Available
No
No